Answer:
A. Oedema and ion imbalance
Explanation:
The proximal tubule is very important to the maintenance of homeostasis in the renal microenvironment. The alterations of the physiological functions will therefore distort the reabsorption of other ions. The blockage of sodium reabsorption into the channel will leads to an hypotonic internal environment. This will afterward leads to reduction of the reabsorption of water into the organ and increase the reabsorption of other ions into it. This will have clinical effect on the organism. Which is oedema of the extracellular surrounding of the tubules through accumulation of fluids and could lead to imbalance in neurological sense due to the imbalance in other ions.
