Even after seemingly complete endoscopic resection recurrence of neoplasia is frequent and independent of additional thermal therapy.
Your answer is D (4)
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Catalysis An enzyme may catalyse a reaction by stressing or
destabilizing the bonds of the substrates. This point in the enzymatic reaction
is known as the Transition State. An
enzyme can couple a nonspontaneous reaction to a spontaneous reaction so that
anabolic processes will occur.