Explanation:
Many mRNAs have sequences of 50 - 150 nt rich in A and U in the 3' untranslated region. These sequences, called AU-rich elements, are important to regulate mRNA stability, because they bind proteins that target the mRNA for degradation.
When a protein binds to the AU-rich element of the mRNA, the polyA tail can be shortened and/or the 5'cap is removed, promoting mRNA degradation. In addition, the AU-rich elements in some mRNAs have been shown to inhibit protein translation.
The mRNA of the overexpressing cell line is about 200nt shorter than the normal cell line; this could mean that it has a deletion in the 3'UTR comprising an AU-rich element. If this is missing, the mRNA will have an extended half-life (because it won't be targeted for degradation) or it will be translated more. As a result, the protein expression will be increased.
Bacteria are prokaryotes and microscopic in size, and they lack a nucleus. DNA is present in the cytoplasm. They do not have membrane-bound organelles.
<h3>What is the size of bacteria?</h3>
- The shapes and sizes of bacteria are extremely diverse.
- The majority of bacteria have a 2–8цm length and a diameter of 0.2-2цm.
- Eukaryotic cells are around ten times larger than bacterial cells.
<h3>What is the difference between prokaryotic and eukaryotic cells?</h3>
- Prokaryotic cells are primitive cells that are primarily present in unicellular organisms; they lack a nucleus but contain a small amount of DNA and do not have membrane-bound organelles.
- In contrast, eukaryotic cells are present in all types of multicellular organisms, including plant and animal cells.
- It possesses a nucleus. All cell organelles are membrane-bound.
- Because they lack a nucleus and other cell organelles and are single-celled microorganisms, they are categorized as prokaryotic organisms.
Bacteria are tiny organisms. They are 200 micrometers in diameter. They do not possess membrane-bound organelles.
Learn more about prokaryotes and eukaryotes here:
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Answer:
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