The cerebrum/cortex - they're the same thing named differently
Florida keys
The Florida keys is a coral cay archipelago in southeast United States.The Florida keys is an island which is near the gulf. The Florida keys is an archipelago landform.
Sea caves
<span>A sea cave,also known as a littoral cave,is a type of cave formed primarly by the wave action of the sea.Sea caves are a coastal and an oceanic landform.A sea cave causes by erosion because the rocks break down then terode all the materials to create sea caves.</span>
Answer:
Amphotericin B
Explanation:
<u>Amphotericin B is the injection which is used to treat potentially life-threatening and serious fungal infections. It is used to treat the fungal infection of nervous system.</u>
It is placed in the class of medications which is known as antifungals. It works by slowing growth of the fungi which cause infection.
Amphotericin B injection is a solid powder which is into solution and injected intravenously into a vein.
Answer:
1. The difference between the normal hemoglobin protein DNA sequence and the sickle cell hemoglobin DNA sequence is a base to base shift, in this case adenine (GAG) to thymine (GTG).
2. The difference affects the amino acid sequence of the protein by replacing glutamic acid (Glu) with valine (Val).
Explanation:
In sickle cell anemia, a change in the DNA nucleotide sequence is observed, where adenine is substituted by thymine, whose expression is the change in the amino acid sequence of globine β, incorporating valine instead of glutamic acid. This represents a molecular mutation - point mutation - by subtitution, which corresponds to missense mutation.
<u>Normal hemoglobin protein in a RBC</u>
DNA CTG ACT CCT GAG GAG AAG TCT
Amino acids Leu Thr Pro Glu Glu Lys Ser
<u>Sickle cell hemoglobin protein in a RBC</u>
DNA CTG ACT CCT <em>GTG</em> GAG AAG TCT
Amino acids Leu Thr Pro <em>Val</em> Glu Lys Ser
When GAG is transcribed to mRNA, the CUC codon is obtained, which codes for glutamic acid. Thymine substitution causes the DNA sequence to change to GTG, which is transcribed as CAC, the codon that encodes the amino acid valine. The <u>change from glutamic acid to valine in β-globin causes an altered hemoglobin, giving the abnormal erythrocytes observed in sickle cell disease</u>.
