The Ca2+ release-activated Ca2+ (CRAC) channel is the most well-documented of the store-operated ion channels that are widely expressed and are involved in many important biological processes. However, the regulation of the CRAC channel by intracellular or extracellular messengers as well as its molecular identity is largely unknown. Specifically, in the absence of extracellular divalent cations, it becomes permeable to monovalent cations with a larger conductance, however, this monovalent cation current inactivates rapidly by an unknown mechanism. Here we found that Ca2+ dissociation from a site on the extracellular side of the CRAC channel is responsible for the inactivation of its Na+ current, and Ca2+ occupancy of this site otherwise potentiates its Ca2+ as well as Na+ currents. This Ca2+-dependent potentiation is required for the normal functioning of CRAC channels.
Current is a flow of electrical charge carriers, usually electrons or electron-deficient atoms.
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A heat is lost to the surroundings
Answer:
c4 is an explosive..
contains RDX, DOS, DOA, and PIB.
Explanation:
Sugar dissolving in warm water because when the sugar dissolves you can get the sugar back by letting the water evaporate.,
The dissolution of CaCl2 in water has an equation written as:
CaCl2 = Ca2+ + 2Cl-
First, we need to calculate how many moles of Cl- we need from the volume and concentration to be used.
mol Cl- needed = 0.0520 mol / L Cl- (2.15 L) = 0.1118 mol Cl-
We can now find how much of the CaCl2 we need as follows:
0.1118 Cl- ( 1 mol CaCl2 / 2 mol Cl-) ( 111.1 g / 1 mol) = 6.21 g CaCl2