Mutations are caused by changes in nucleotide bases. these altered base formed different amino acid depending upon nucleotide base sequence that code specific amino acid. ... even though some mutations, can have a more effect on amino acid coding, which can affect what kind of proteins are produced.
Red cells take up 40%-50% of the total blood volume
This definition above refers to the geographic isolation.
It means exactly what it says in the definition - one species is left behind from the rest of the population, and it stays in that particular location, evolving and changing from the species and population it was once a part of.
Basement membranes are thin, dense sheets of specialized, self- assembled extracellular matrix that surround most animal tissues. The basement membrane is a fibrous matrix composed primarily of glycoproteins, type IV collagen, and laminin that are secreted by the epithelial cells.