Langerhans cells are dendritic cells (antigen-presenting immune cells) of the skin, and contain organelles called Birbeck granules. They are present in all layers of the epidermis and are most prominent in the stratum spinosum.
It depends on what type of disease it is, most people won’t believe you until you can scientifically prove you can
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The major criteria for custom provisional fabrication is done by making preliminary impression and by making a cast preparation prior to tooth preparation. These steps are essential to fabrication process.