<span>The answer is a certain required chemicals must be actively
transported. Blood brain barrier is a
selective membrane that separates blood circulating from the brain and the
fluid of extracellular in the central nervous system. This is also called a
filtering mechanism, the capillaries that carry blood to the brain and spinal
cord tissue blocking the path way of the certain substance.</span>
<span>Prokaryotes are divided into 2 domains: bacteria and the archaea (or Archaebacteria).</span>