The answer is that it means that the oxygen would be difficult to carry throughout the body, which happens that ATP would be lacking. Because to create energy there’s a need for respiration and it requires an oxygen. Also, other body systems will slow down because anaerobic respiration doesn't create enough ATP for the entire body.
The correct answer is Alcoholic dementia.
Alcohol-related dementia (ARD) is a type of dementia brought on by prolonged, excessive alcohol use, which damages the brain and impairs cognitive function.
Wet brain, sometimes referred to as Wernicke-Korsakoff syndrome, is another type of ARD that is characterized by short-term memory loss and thiamine (vitamin B1) deficiency.
Patients with ARD frequently exhibit both type's symptoms, such as memory loss, apathy, and impaired planning. ARD may coexist with different types of dementia (mixed dementia). Despite being widely accepted, the diagnosis of ARD is only occasionally used because there aren't any clear diagnostic criteria.
Hence, the patients with generalized loss of brain tissue due to direct consumption of alcohol suffers from alcoholic dementia which causes memory loss and many other problems.
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I'm not 100% sure, but I'd say the availability of vaccines and medicine.