This inhibition is restricted to bacterial translation because; the peptidyl transferase is an enzyme aminoacyltransferase as well as the primary enzymatic function of the ribosome, which forms peptide bonds between adjacent amino acids using tRNAs during the process of translation. Therefore, inhibition of this enzyme means that the process oof translation wont take place, hence proteins will not be formed and thus the bacteria will die.
Answer:
1. P120 is degraded in the 26S proteasome
2. The 26S proteasome has a major role in protein degradation and is critical for protein homeostasis
3. Cell cycle and DNA replication are cellular processes regulated by the Ras and NFkB pathways
Explanation:
The proliferation-associated nucleolar protein (p120) is a protein known to be expressed during the interphase of the cell cycle, specifically in G1 and early S phase, where any problem with DNA replication trigger a checkpoint, i.e., a molecular cascade of signaling events that suspend DNA replication until the problem is resolved. In mammalian cells, the 26S proteasome is responsible for catalyzing protein degradation of about 80% (or even more) of their proteins. The 26S proteasome acts to degrade rapidly misfolded and regulatory proteins involved in the cell cycle, thereby having a major role in protein homeostasis and in the control of cellular processes. It is for that reason that inhibitors that block 26S proteasome function have shown to be useful as therapeutic agents in diseases associated with the failure of protein degradation mechanisms (e.g., multiple myeloma). The NF-κB are highly conserved transcription factors capable of regulating different cellular processes including, among others, cellular growth, inflammatory responses and apoptosis. Moreover, the MAPK/ERK pathway is able to transduce different signals received on the cell surface to the nucleus. The MAPK/ERK pathway is activated when a singling molecule binds to a cell receptor which triggers a signaling cascade that ends when a transcription factor induces the expression of target genes, ultimately producing a response in the cell (for example, the progression through the cell cycle).
Answer:
Enzymes help the most in the digestion of food.
<em> - Hope this helps!</em>
Answer:
Among the seven characteristics in life, the one should be sensitivity. It is where living organisms detect and react to stimulus or changes to the environment.
Specifically among plants, this change is called a tropic response, or tropism for short. Plants reacts to aspects like light, gravity, or water.
This response is controlled by a plant hormone called auxin. Auxin is produced at the tip of the plant, and they diffuse among the plant. The auxin accumulates at the side of the plant that doesn't receive as much sunlight, and auxin can stimulate its growth on that side so the plant bends. That's how a plant bending works.
Anyways, the answer to the question should be sensitivity.
