The first one. Gametes are the reproductive cells: sperm and egg cells. These contain the info that is passed on to the offspring, so an inherited mutation must be present in the gametes.
HCL is guilty for triggering the release of enzymes such as pepsin which are essential for the digestion of protein. Bile contains bile acids, which are critical for digestion and absorption of fats and fat-soluble vitamins in the small intestine.
