Answer:
The Various Kinases that is activated after the breaks in DNA is after the activation of ATM serine threonine kinase which helps in phosphorylation of other DNA replication check proteins, p53 protein (tumor suppressor protein) etc.
Explanation:
ATM activated by MRN complex at the site of DNA double stranded breaks by phosphorylation. MRN complex activity on ATM induces a conformational change in ATM kinase. So it can bind to its various substrate molecules that helps in DNA replication cycle arrest.
ATM phosphorylates CHK2 protein a product of CHEK2 gene, also known as effector kinases that phosphorylates and helps in deactivation of cyclin dependent kinases (CDKs) that helps in the prevention of progression of mitotic phase.
ATM also phosphorylates the inhibitors of p53 proteins which leads to the overexpression of p21, an inhibitor of (CDKs).
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Nucleotides are the building blocks of nucleic acids. In DNA, there are four types of nucleotides each containing one of four nitrogenous bases: guanine (G), cytosine (C), adenine (A), thymine (T).
- The monomer exhibited in the figure is a NUCLEOTIDE, i.e., a purine (Adenine) nucleotide.
- A nucleotide is a molecule composed of a nitrogenous base, a pentose sugar (deoxyribose in DNA) and a phosphate group.
- Purine bases consist of a double‐ring structure having four nitrogen (N) atoms and five carbons (C) atoms.
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Gasoline igniting doesnt change physically, wood rotting is just it getting old i guess, i would say d because its from water to vapenation. im really bad in school so im not sure but i decided to answer
The answer would be beta blocker.
Beta blocker is an antihypertensive drug that works by <span>decreasing norepinephrine release. The reduce of norepinephrine would prevent vasoconstriction and increased heart rate. This two effect contribute to the orthostatic hypotension the patient describe.
Some of the drugs are lipophilic which means it can pass blood </span>brain barrier, cause some effect like vivid dreaming. That is why the drug best to take on morning, not evening.
