When a nerve impulse reaches the end of an axon, the axon terminal released ACh into the synaptic cleft. 2. ACh diffuses across the cleft and attaches to the ACh receptors on the sarcolemma of the muscle fiber. 3. ACh binding triggers electrical events that ultimately generate an action potential.
Mutations in the nucleic acid sequence of the gene that can be sometimes direct the substitution of one amino acid for another in the encoded protein. Arginine and methionine amino acid are the substitution that would be most likely to severely disrupt the normal structure of the protein
A genetic mutation is the change to a gene's DNA sequence that produce something different. It also creates a permanent change to that gene's DNA sequence. Genetic variations are the important for the humans to evolve, which is the process of change over the generations. A sporadic genetic mutation may occurs in one person.
A mutation is a change in the DNA sequence of the organism. Mutations can result from the errors in the DNA replication during the cell division, exposure to the mutagens or the viral infection.
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