Answer:
A mutation in <u>DNA </u>results in a change in <u>RNA </u>that sometimes produces a <u>protein </u>with altered structure and function.
Explanation:
DNA is the hereditary material which causes gene expression in our body by producing protein. The type of protein which is produced by DNA totally depends upon the sequence of nucleotides in the DNA. But, DNA molecule does not produce protein directly. Initially it produces RNA (mRNA, tRNA, rRNA) by the process of transcription, the nucleotides in the RNA are complimentary to those in DNA. In short, the message regarding the structure and composition of the type protein to be produced by DNA is first decoded from DNA in the form of RNA. These RNA molecules then synthesize the protein as per the instructions from DNA by the process of translation.
But, in case a mutation occurs in the DNA which causes a change in it's nucleotide/nucleotides, the protein which will be produced will be different in the structure and function than the protein which was supposed to be synthesized. It happens because, a triplet of nucletiodes in the DNA and hence RNA specifies a particular type of amino acid and several amino acids are joined in a long chain to form polypeptide which ultimately forms protein. But, if any nucleotide in the triplet is changed due to mutation it may change the amino acid and if amino acid will change the protein will also get altered.
The main structural difference between LDL and HDL is their compositions. Approximately 50% of the weight of an LDL particle is cholesterol and only 25% is protein. High-density lipoprotein particles, on the other hand, consist of 20% percent cholesterol by weight and 50% protein.
Enzymes are protein macromolecules.
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