Disruption of axonal transport would be a good target for his drug.
<h3>What is disruption of axonal transport?</h3>
- Axonal transport defects are among the early molecular events leading to neurodegeneration in mouse models of amyotrophic lateral sclerosis (ALS).
- Gene expression profiles indicate that dynactin-1 mRNA is downregulated in degenerating spinal motor neurons of autopsied patients with sporadic ALS.
- Disruption of axonal transport also underlies the pathogenesis of spinal muscular atrophy and hereditary spastic paraplegias.
- The neurotoxin β,β′-iminodipropionitrile (IDPN) selectively disrupts slow axonal transport without affecting fast anterograde or retrograde axonal transport.
- Impairment of slow axonal transport causes a proximal accumulation of neurofilaments.
- Because neurofilaments regulate axonal diameter, this accumulation leads to a marked swelling of the axon.
- Acrylamide causes decreased axonal transport, also causing proximal accumulations of neurofilaments and swelling.
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Answer:
As light intensity increases (distance between lamp and plant decreases) the volume of oxygen (or the rate of bubble production) increases. This indicates that the rate of photosynthesis increases with light intensity. However, at sufficiently high levels of light intensity, the rate oxygen evolution remains constant.
Answer:
Rr x rr
Explanation:
Let's say
RR is a tall plant.
Rr is tall
& rr is a small plant
The only genotypes you can get to make two tall and two short is if you use a hetero pair and a same ressesive (rr) genes.
