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eduard
3 years ago
7

What bio chemical reactions are altered due to Down syndrome

Biology
1 answer:
ryzh [129]3 years ago
5 0

Answer:

Abstract

Down syndrome (DS) is associated with aberrations in genetic, morphological, biochemical and physiological characteristics. A number of genes located on human chromosome 21 (HSA21) encode proteins which are thought to be involved in numerous metabolic pathways, e.g., phosphofructokinase, cystathionine β-synthase etc. Perturbations of the metabolic pathways may lead to altered drug metabolism in DS individuals. We present a review of metabolic aberrations linked to HSA21 genes in DS. We particularly focus on drug disposition, efficacy, sensitivity and toxicity of anti-leukaemic agents including methotrexate, glucocorticoids, anthracyclines and cytarabine in DS leukaemia. The different outcomes of therapy due to differential drug response, varied drug toxicity and treatment related mortality in DS leukaemia is a subject of much research and speculation. Altered drug response in DS individuals may stem from differences in pharmacokinetics, pharmacodynamics and pharmacogenetics. Further large-cohort studies in different age groups dissecting metabolic and molecular pathways involved in drug response may increase our understanding in this regard and stipulate pharmacotherapies in DS.

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Explanation:

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describe the relationship between the functions of endosymbiotic organelles and their free-living ancestral counterparts
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Learn more about endosymbiotic here;-brainly.com/question/1698852

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7 0
1 year ago
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sleet_krkn [62]

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7 0
3 years ago
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patriot [66]
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In other words, we can also say that taxon is also known as a taxonomic group of any rank, such as a species, family, or class. It is a group of one or more than one different populations of an organism or the organisms viewed by taxonomists to make a system. These are the rules for naming new animals.

<h2>(Answer 2 points 3)</h2><h2>B. Taxonomy</h2><h3>1. the science of the classification of organisms.</h3><h2>Explanation:</h2>

A taxonomy is said to be a scheme of classification or in other words, we can also define the term taxonomy as the branch of science involved with classification, especially of organisms, systematics. Organisms are grouped together. This science of gives name, describe and classify the organisms including all the plants, animals and the microorganisms of the world.

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Family is the one that has been classified between order and genus. A family is also divided into the subfamilies. It is one of the eight main and important taxonomic levels. It is a primary taxonomic category of organisms ranking. This category comes on the sixth number of all the categories lies in a taxonomic group.

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4 0
3 years ago
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