DNA ligase is the enzyme that repair irregularities and breaks in the back bone of double stranded DNA. The enzyme function by sealing the repair in the DNA, it seals recombination fragments and it connects okazaki fragments during replication of DNA.
If a mutation reduce the amount of ligase, all the functions of the ligase enzyme listed above will be affected negatively.
Warm Front would be your answer
Is the question multiple choice?
Because water cant breath and it doesn't have feelings.<span />
The third answer. The weight loss of the patients might have been due to other things and there is no provable coloration until an experiment is conducted.