Question

Is it true that the breakdown of food molecules in the gut does not require coupling of atp hydrolysis, but enzymes are required to speed up the spontaneous reaction?

Answer 1

The statement is true.  Digestion of food molecules in the digestive system in the gastrointestinal tract does not require coupling of ATP hydrolysis; but instead requires enzymes that speed up the spontaneous reaction. Enzyme digest specific food substrates at different parts of the digestive system until the final useful products of these enzymatic reactions are absorbed to the body metabolism.