Answer:
q = 0.42
Explanation:
This question is an example of Hardy-Weinberg question and there are two equations necessary to carry out this question;
p + q = 1
p² + 2pq + q² = 1
where;
p = the frequency of the dominant allele
q = the frequency of the recessive allele
p² = the frequency of individuals with homozygous dominant genotype
2pq = the frequency of individuals with heterozygous genotype
q² = frequency of individuals with the homozygous recessive genotype
Since the total population = 425
q² = 
= 
q² = 0.1765
To find q; we need to square root both side to eliminate the square from q².
∴ 
q = 0.4201
q = 0.42 (to two decimal places)
Caffeine cause dose dependent prominent increase in force of contraction and period of contraction of muscle
<u>Explanation:</u>
Caffeine is widely used in foods and drinks. Its long time use can effect central nervous system include lethargy memory, sleep disorder and anxiety.
Increase in concentration of calcium ion will result increase number of power stroke and force for contraction. However latent period and relaxation period are unaffected by caffeine. Increase in concentration of calcium ion will result increase number of power stroke and force for contraction.
Because of calcium ion release in skeletal muscle, caffeine causes peripheral manifestation such as hyper-reflexia, muscle twitching etc.
High amount of caffeine leads to increase in release of Ca2+ from sarcoplasmic reticulum. It increases tension development in single tetanic contraction and re-initiate maximum tension in fatigue single myofibre by restoring Ca2+ release from sarcoplasmic reticulum to non-fatigued levels.
