The order is calcification of matrix >> cells differentiate into osteoblasts >> formation of the primary ossification >> osteoclasts break down the spongy bone >> formation of the secondary ossification (5,3,1,2,4). It is a fundamental process.
<h3>What are osteoblasts?</h3>
Osteoblasts are cells of the bones, which act to generate bone matrix and modulate the process of mineralization of the skeleton.
Endochondral ossification refers to the mechanism through which the cartilaginous bones generate longitudinal growth.
This mechanism (endochondral ossification) is fundamental during fetal/embryo development.
Learn more about endochondral ossification here:
brainly.com/question/5325975
Answer:
Option A, a drug to treat high blood pressure that reversibly inhibits an enzyme catalyzing production of a chemical that causes blood vessels to contract
Explanation:
The complete question is
If you were working for a pharmaceutical company as part of a drug discovery team, which of these enzyme inhibitors would you suggest as a productive avenue for drug development?
a) a drug to treat high blood pressure that reversibly inhibits an enzyme catalyzing production of a chemical that causes blood vessels to contract
b) a drug to treat diabetes that irreversibly inhibits an enzyme in the metabolic pathway to synthesize glucose
c) a compound that acts as a competitive inhibitor for a digestive enzyme produced only in the presence of certain foods
d) a compound that inhibits enzymes by significantly changing the ph throughout the body
Solution
Productive avenue of a drug simply means producing an drug that not only treats the main disease or disorder but also functions to inhibit the causative agent activity. In case of option A, both the objectives of producing drug are met and hence it is the right choice.
High blood pressure usually affects the blood vessels by narrowing them and in severe cases may rupture them. If a drug as stated in option A is produced, it will not only rectify the effects of high blood pressure but will also prevent the blood vessels from narrowing by inhibiting the activity of enzymes responsible for producing chemical that leads to blood vessel contraction.
Hence, option A is correct
Plant #1 would locate in a damp and probably contain no undergrowth. Example forest.
Plant #2 would locate in a dry area such as a desert example cactus, as the waxy coating keeps water and the spines suck up water and protect the plany
The nine activities that scientists engage in as a part of scientific inquiry are the following:
1. Observe
2. Define the problem
3. Form a study question
4. Research the problem
5. State the expectations (hypothesis)
6. Experiment and gather data
7. Analyze the results
8. Reflect on the findings
9. Communicate with the wider community