Defects in transcription factors underlie some forms of cancer.
Seeing as Peter is male, he's seeing a counselor (which indicates mental/emotional/psychological issues) and has been referred to a urologist, I'd say his problem is erectile dysfunction, or choice #2.
In the thylakoids of the grana, light reactions take place and in the stroma , dark reaction takes place. So all in all, in both places together photosynthesis is carried out
