Answer:
Sickle cell disease in an autosomal recessive inherited disease which is caused by the mutation in the HBB (hemoglobin-β gene) gene present on the chromosome no. 11. In sickle cell, the red blood cells become sickle shape due to the abnormal shape of hemoglobin present in it.
These sickle cells are known to form a blockage in the blood vessels thereby causing damage to the vital organs. Human spleen constantly destroys sickle cells because they get trapped in it which causes a disease called sickle cell anemia.
Sickle cell anemia is normally the problem in genetic disease which is inherited from the parents to children. When both the DNA strand has a mutation in their HBB gene then only this disease will affect the individual.
Answer:
The sequence of amino acids. - The three-dimensional shape of the folded protein. - If the coding sequence has a mutation that leads to a change in the amino acid sequence, the protein may have a different three-dimensional shape, reducing its activity.
Explanation:
Answer: Leu (leucine)
Explanation: The mRNA code for a DNA strand of AAT is UUA. The amino acid that UUA codes for is Leu, short for leucine (I don't know if you need the full name of it).
GENE controls traits and inheritance