Strange question, as normally we would not calculate the "area of the tire." A tire has a cross-sectional area, true, but we don't know the outside radius of the tire when it's mounted on the wheel.
We could certainly calculate the area of a circle with radius 8 inches; it's
A = πr^2, or (here) A = π (8 in)^2 = 64π in^2.
The circumference of the wheel (of radius 8 in) is C = 2π*r, or 16π in.
The numerical difference between 64π and 16π is 48π; this makes no sense because we cannot compare area (in^2) to length (in).
If possible, discuss this situatio with your teacher.
