There are three things.... The margins of the drifting continents, the existence of matching rock types and formations and the presence of similar fossils on opposing edges!
Hope this helps ya out! :)
When chemical substances such as perfume are let loose in a room, their particles mix with the particles of air. The particles of smelly gas are free to move quickly in all directions. They eventually spread through the whole room from an area of high concentration to an area of low concentration.
Different enzymes have specific active sites which can only catalyze one <span>substrate. Enzyme-substrate complexes are produced only when the substrate fits into the active site :)</span>