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Vikki [24]
2 years ago
13

How does flouride cause kidney deasies

Biology
1 answer:
SCORPION-xisa [38]2 years ago
6 0

Answer:

Hepato- and nephrotoxicity of fluoride have been demonstrated in animals, but few studies have examined potential effects in humans. This population-based study examines the relationship between chronic low-level fluoride exposure and kidney and liver function among United States (U.S.) adolescents. This study aimed to evaluate whether greater fluoride exposure is associated with altered kidney and liver parameters among U.S. youth.

This cross-sectional study utilized data from the National Health and Nutrition Examination Survey (2013–2016). We analyzed data from 1983 and 1742 adolescents who had plasma and water fluoride measures respectively and did not have kidney disease. Fluoride was measured in plasma and household tap water. Kidney parameters included estimated glomerular filtration rate (calculated by the original Schwartz formula), serum uric acid, and the urinary albumin to creatinine ratio. Liver parameters were assessed in serum and included alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, blood urea nitrogen, gamma-glutamyl transferase, and albumin. Survey-weighted linear regression examined relationships between fluoride exposure and kidney and liver parameters after covariate adjustment. A Holm-Bonferroni correction accounted for multiple comparisons.

The average age of adolescents was 15.4 years. Median water and plasma fluoride concentrations were 0.48 mg/L and 0.33 μmol/L respectively. A 1 μmol/L increase in plasma fluoride was associated with a 10.36 mL/min/1.73 m2 lower estimated glomerular filtration rate (95% CI: −17.50, −3.22; p = 0.05), a 0.29 mg/dL higher serum uric acid concentration (95% CI: 0.09, 0.50; p = 0.05), and a 1.29 mg/dL lower blood urea nitrogen concentration (95%CI: −1.87, −0.70; p < 0.001). A 1 mg/L increase in water fluoride was associated with a 0.93 mg/dL lower blood urea nitrogen concentration (95% CI: −1.44, −0.42; p = 0.007).

Fluoride exposure may contribute to complex changes in kidney and liver related parameters among U.S. adolescents. As the study is cross-sectional, reverse causality cannot be ruled out; therefore, altered kidney and/or liver function may impact bodily fluoride absorption and metabolic processes.

hope this helps

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N which vertebrates did feathers first evolve?
Lapatulllka [165]
<span>Wings have evolved several times independently. In flying fish, the wings are formed by the enlargement of the pectoral fins. Some fish leap out of the water and glide through the air, both to save energy and to escape predators. If they were already gliding, then any mutation that would result in an increase of the gliding surface would be advantageous to the fish that has it. These advantageous may allow these fish to out-compete the others. 

Wings have also evolved in bats, pterosaurs, and birds. In these animals, the wings are formed by the forelimbs. In some lizards that have evolved gliding flight, however, the "wings" or gliding surfaces may be quite different. The lizard Draco, for example, has gliding surfaces formed by an extension of the ribs. A number of extinct reptiles have similar gliding surfaces. Frogs that glide have expanded webbing on their hands and feet. Gliding ("flying") squirrels and marsupial sugar gliders have flaps of skin that lie between the front and rear limbs. These gliding animals all have one thing in common: a gliding surface that is formed by enlarging some parts of the body. 

In pterosaurs, the wing is formed by an elongated finger and a large skin membrane attached to this finger. In bats, the wing is formed by the entire hand, with skin membranes connecting the elongated fingers. In birds, flight feathers are attached to the entire forelimb, while the fingers have fused together. In all of these animals except birds, the wing is a solid structure. In birds, however, the wing is formed by a large number of individual feathers lying close to each other and each feather is in turn formed by filaments that interlock. 

Biophysicists have determined that flight most likely evolved from the tree down. That means most active flyers evolved flight from an animal that was already gliding. Gliding was therefore probably an indispensable intermediate stage in the evolution of flight. Since gliding has evolved in so many different groups of animals, it follows that the ancestors of birds, bats, and pterosaurs were almost certainly gliders. 

Unfortunately, the fossil records of the immediate gliding ancestors of birds, bats, and pterosaurs are all missing. The first known bat and bird fossils are recognizable as flyers. The same is true of pterosaurs. Therefore the origin of these flyers remain a mystery and a subject of often acrimonious debate. There are people who claim that dinosaurs evolved insulation, which then evolved into feathers, but the evidence for that is lacking. The so-called proto-feathers found on some dinosaurs are indistinguishable from the collagen fibers found in the skin of most vertebrates. Some of the supposedly feathered dinosaurs, such as Caudipteryx and Protarchaeopteryx, are actually flightless birds. The same is probably true of Microraptor fossils, which are (as Alan Feduccia says) probably "avian non-dinosaurs." 

Even though the immediate ancestor of birds remains a mystery, there is a fossil known as Longisquama insignis, which lived during the late Triassic. It has featherlike structures on its back. It was probably a glider of some sort. So, this animal may well be the distant ancestor of Archaeopteryx, the oldest known bird. 

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See link below for details of why dinosaurs are considered ectothermic according to the available scientific evidence.</span>Source(s):<span>http://discovermagazine.com/1996/dec/aco...</span>
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<h3><u>Explanation</u>:</h3>

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This pseupodia engulfs the food and performs phagocytosis or pinocytosis. This food is covered in a cell membrane inside the cytoplasm which is called the food vacoule or endosome. This then fuses with a lysosome to digest and then the excretory product is let off by the secondary vacoule.

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schepotkina [342]

Answer:

The answer is A

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Because he scolded her

I hope this helps! :)

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Have a nice day!

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