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Vikki [24]
2 years ago
13

How does flouride cause kidney deasies

Biology
1 answer:
SCORPION-xisa [38]2 years ago
6 0

Answer:

Hepato- and nephrotoxicity of fluoride have been demonstrated in animals, but few studies have examined potential effects in humans. This population-based study examines the relationship between chronic low-level fluoride exposure and kidney and liver function among United States (U.S.) adolescents. This study aimed to evaluate whether greater fluoride exposure is associated with altered kidney and liver parameters among U.S. youth.

This cross-sectional study utilized data from the National Health and Nutrition Examination Survey (2013–2016). We analyzed data from 1983 and 1742 adolescents who had plasma and water fluoride measures respectively and did not have kidney disease. Fluoride was measured in plasma and household tap water. Kidney parameters included estimated glomerular filtration rate (calculated by the original Schwartz formula), serum uric acid, and the urinary albumin to creatinine ratio. Liver parameters were assessed in serum and included alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, blood urea nitrogen, gamma-glutamyl transferase, and albumin. Survey-weighted linear regression examined relationships between fluoride exposure and kidney and liver parameters after covariate adjustment. A Holm-Bonferroni correction accounted for multiple comparisons.

The average age of adolescents was 15.4 years. Median water and plasma fluoride concentrations were 0.48 mg/L and 0.33 μmol/L respectively. A 1 μmol/L increase in plasma fluoride was associated with a 10.36 mL/min/1.73 m2 lower estimated glomerular filtration rate (95% CI: −17.50, −3.22; p = 0.05), a 0.29 mg/dL higher serum uric acid concentration (95% CI: 0.09, 0.50; p = 0.05), and a 1.29 mg/dL lower blood urea nitrogen concentration (95%CI: −1.87, −0.70; p < 0.001). A 1 mg/L increase in water fluoride was associated with a 0.93 mg/dL lower blood urea nitrogen concentration (95% CI: −1.44, −0.42; p = 0.007).

Fluoride exposure may contribute to complex changes in kidney and liver related parameters among U.S. adolescents. As the study is cross-sectional, reverse causality cannot be ruled out; therefore, altered kidney and/or liver function may impact bodily fluoride absorption and metabolic processes.

hope this helps

rate brainiest

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Provide brief overview of the nervous system and its role in the maintenance of homeostasis.
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The nervous system has two major anatomical subdivisions:

Central Nervous System: Composed of the brain (inside the skull) and the spinal cord (inside the spinal column).

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Peripheral nervous system: it is everything that is outside the bone cavity and is formed by the nerves and nerve ganglia that extend outside the central nervous system.

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On the other hand, the autonomic nervous system is a component of the peripheral nervous system that regulates involuntary physiological processes. These processes include heart rate, blood pressure, breathing, digestion, and sexual arousal. The autonomic nervous system contains three divisions: sympathetic, parasympathetic, and enteric.

Due to the above relationships and anatomical subdivisions we can say that the nervous system is responsible for regulating and maintaining homeostasis. In fact, through its receptors, neurotransmitters, nervous inputs, and outputs, the nervous system keeps us in touch with our environment, both external and internal.

We can conclude that the correct answer is:

Answer:

Overview of the nervous system:

The nervous system has two major anatomical subdivisions:

Central Nervous System: Composed of the brain (inside the skull) and the spinal cord (inside the spinal column).

The brain and spinal cord are responsible for processing and integrating the various sources of information to allow us to develop a response. Therefore, the main function of the somatic nervous system is to connect the Central Nervous System with the organs and skeletal muscle to carry out our daily functions.

Peripheral nervous system: it is everything that is outside the bone cavity and is formed by the nerves and nerve ganglia that extend outside the central nervous system.

The peripheral nervous system has a somatic component, which is associated with the voluntary control of body movements through the use of skeletal muscles. This means that it is responsible for all the functions that we are aware of, including the movement of our arms, legs, and other parts of our body.

On the other hand, the autonomic nervous system is a component of the peripheral nervous system that regulates involuntary physiological processes. These processes include heart rate, blood pressure, breathing, digestion, and sexual arousal. The autonomic nervous system contains three divisions: sympathetic, parasympathetic, and enteric.

Role in the maintenance of homeostasis:

Due to the above relationships and anatomical subdivisions we can say that the nervous system is responsible for regulating and maintaining homeostasis. In fact, through its receptors, neurotransmitters, nervous inputs, and outputs, the nervous system keeps us in touch with our environment, both external and internal.

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