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Enzymes can be reused over and over again
When we're doing scientific research, we should definitely be avoiding any sources which aren't scientific by nature. This means we should avoid sources which haven't been peer reviewed by fellow authors of a similar field. With this, we avoid using literature of questionable quality.
Answer: Coenzymes
Explanation:
Coenzymes are the small organic molecules that are often derived from the vitamins. It can be tightly or loosely bond to the enzymes.
Tighly bond ones are the prothestic groups and loosely bond ones are coenzymes like the products and substrate which binds to the enzyme and get released from it.
This component is very important for any reaction to take place. It bonds to the enzymes and helps in product formation.
Im not 100% sure but the best answer I can give is Prokaryotes because they came to be around the time oxygen did as well.