* More than 40 proteins and glycoproteins involved in the complement system are synthesized by the liver, macrophages, epithelial cells, they are present in the blood in plasmatic form, membrane, some have an enzymatic activity, regulator or membrane receptorThese are elements of the humoral innate immune response, they fight infections, purify immune complexes and apoptotic bodies.
<span>There are indeed three ways to activate the complement:</span>
Classical pathway: Activated by Immunoglobulins in immune complexes, aggregated Immunoglobulins, DNA, CRP, apoptotic bodies .......it involves nine fractions, starting with C1, then C4, C2, C3, to form a classical C5 convertase, then, activation of C5, C6, C7, C8, C9.
Alternative pathway: activated by polysaccharides (bacterial endotoxin), vascular wall poor in sialic acid, aggregated IgE ...C3b like is the first component in the alternate channel cascade, it will create an amplification loop, and form an alternative C5 convertase.
Lecithin pathway: Activated by mannose, fucose (carbohydrate of microorganisms)The first component is the complex MBL / MASP1 / MASP2: "mannose-binding protein": works according to the same principle as the complex C1 of the classical way (MASP2 cleaves the C4 and the rest of the cascade is equivalent to that of the classical way).
the three ways have the same outcome: A C5 convertase (formed by one of the pathways) cleaves C5 into C5a and C5b: C5b is deposited far from other fractions on the antigenic surface. The fixation of C5b in the cell is followed by that of C6, C7, C8, and C9 (9 molecules of C9): formation of the membrane attack complex (MAC) ==> Death of the cell by osmotic shock
The correct answer is E. Vertebrates are all related to a common ancestor
Explanation:
According to biology and evolution, organisms from different species but that share similarities in morphology (body structures) as well as in genetics often have a phylogenetic relationship which means they descend from the same organism or share a common ancestor. This applies to multiple taxonomical levels including classes such as mammals or birds as it has been proved each of this derived from a common ancestor. Therefore, the similarity in the body structure (morphology) in all mammals suggest vertebrates are related to a common ancestor and as they evolved from this, they share similarities not only in terms of morphology but also in genetics.
Answer:
Bones provide the structure for our bodies. The adult human skeleton is made up of 206 bones.
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Answer:
Everyone can understand what animal someone is referring to when they use the international name for the organism.
Explanation:
Since everyone uses different languages around the world, the international system helps such that they can understand each other without any language barriers and they can also quickly know which class the organism belongs to.
Answer:
90N
From the above question, we are given the mass , acceleration and required to find the force
from Newton's law we know that
F= ma
