<h2>KDEL Sequence & Protein Unfolding</h2>
Explanation:
(a) The distinction between proteins sent out from and those held in the ER has all the earmarks of being represented by two unmistakable sorts of focusing on successions that explicitly mark proteins as either bound for transport to the Golgi or bound for maintenance in the ER. Numerous proteins are held in the ER lumen because of the nearness of the focusing on grouping Lys-Asp-Glu-Leu (KDEL, in the single-letter code) at their carboxy end. In the event that this succession is erased from a protein that is regularly held in the ER (e.g., BiP), the transformed protein is rather moved to the Golgi and emitted from the cell. On the other hand, the expansion of the KDEL arrangement to the carboxy end of proteins that are typically discharged makes them be held in the ER. The maintenance of some trans membrane proteins in the ER is comparatively directed by short C-terminal successions that contain two lysine deposits (KKXX sequences)
(b) Proteins are large molecules composed of folded chains of amino acids. Every protein has a unique shape and that shape determines the things it does. You could think of them as keys that fit into certain locks around the body Proteins do lots of different things around the body, including speeding up biological processes, recognizing antibodies, providing structure to certain body parts, transporting substances, regulating genes, and responding to signals inside and outside the body Proteins range in size from small ones, such as insulin - only 51 amino acids long, to extremely large ones, such as titin almost 27,000 amino acids long. No matter their size, they must be folded into a particular shape in order to function. Sometimes, though, things go wrong and cause the protein to unfold
Answer:
epidermis
Explanation:
The epidermis is the protective outer layer of clonally related cells covering all plant organs. and the outer most layer in animals is no
The smallest blood arteries in the lungs leak fluid into the tiniest air sacs where the blood is oxygenated, which is the mechanical cause of ARDS.
<h3>
What is the causes of ARDS?</h3>
Sepsis, a dangerous and widespread bloodstream infection, is the most typical cause of ARDS. breathing in dangerous toxins. ARDS may develop as a result of breathing toxic gases, excessive smoke concentrations, aspirating vomit, or near-drowning incidents. acute pneumonia.
Sign of respiratory distress
- Breathing rate.
- Color changes.
- Grunting.
- Nose flaring.
- Retractions etc.,
Learn more about respiratory distress here:
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1. The answer is Density
2. Two ways to make peace with your body are to create a positive mental outlook and to give yourself credit
3.When on a weight-gain diet, untrained men tend to initially gain about 2 pounds of muscle per month, and 20 pounds or more per year. This is because there is more area in the body available for muscle growth that's why muscle fibers are easily developed and recruited to perform muscle contractions.
4. <span>figure out where in your day you could eat more food.
5. amino acids
6. weight
</span>
Until recently, prokaryotes did not contain linear plasmids or chromosomes, but they have since been discovered in spirochaetes, Gram-positive bacteria, and Gram-negative bacteria. Bacterial linear DNA has been classified into two structural kinds. Each end of linear plasmids from the spirochaete Borrelia has a covalently closed hairpin loop, while each end of linear plasmids from the Gram-positive filamentous Streptomyces has a covalently connected protein. In eukaryotic cells, replicons with comparable structures are more common than in prokaryotes. However, linear genomic architectures are likely more widespread in bacteria than previously thought, and some replicons may be able to switch between circular and linear isomers. The molecular biology of these widely scattered pieces reveals information about the origins of linear DNA in bacteria, including evidence of prokaryote-eukaryotes genetic exchange.
