Clotting cascade refers to the series of reactions which take place simultaneously and result in blood clotting. The clotting cascade is a complex set of negative feed back mechanism which is used by the human body to maintain homeostasis. The clotting cascade can be triggered either by intrinsic or extrinsic release of chemical mediators. The reaction occur in this order:
Intrinsic factor < activation of common clotting pathway < platelet lipids are released < prothrombin < fibrinogen < fibrin formation < stabilized fibrin clot.
Two examples of anticoagulant medication that affect the pathway are heparin and warfarin
Used by American pioneers living in the Great Plains in the 19th century. The emigrants traveled by wagon in search of fertile land in Oregon's Willamette Valley.
Bioaccumulation is the process by which chemicals are stored in the tissues of living organisms. It is the accumulation of chemicals in the tissue of organisms through any route including, respiration, ingestion or direct contact with contaminated water, sediment and pore water in the sediment. These chemical substances include, pesticides or other chemicals.
