Answer:
The E zone portion of the protein
Explanation:
The glucagon hormone which is a signal molecules that triggers a reaction in the liver cells is most likely to bind to the E zone extracellular portion of the G-protein-coupled receptor. This then changes the conformation of the receptor activating the heteromeric G proteins.
Disruption in the intercalated discs in the cardiac muscles would interfere with the hearts ability to beat in synchronous manner.
The important salient features of intercalated disc are-
- These intercalated disc in cardiac muscles of the heart create connections between nearby cells
- The intercalated disc provides for coordinated operation of the cardiac cells and is highly specialised to facilitate the beating
- Extensive folds and intercellular junctions for mechanical and electrical interactions between neighbouring cells make up the intercalated disc at the ends of muscle cells
The electrical characteristics of the cardiac muscle cells and the passage of electrical information from one region of the heart to another determine the rate at which the heart contracts and the synchronisation of atrial and ventricular contraction necessary for the efficient pumping of blood.
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Scientific resolution important mircoscope samples
Answer:
The type of vesicular transport involved in the exporting of protein-based hormones, such as insulin, into the bloodstream is regulated exocytosis.
Explanation:
In general terms, exocytosis is a type of active transport that allows intracellular substances are released to the extracellular space, through of vesicles that fuse with the plasma membrane, which allow the exit of substances from inside the cell.
Regulated exocytosis is the specific vesicular transport for the secretion of substances, such as hormones. For this type of transport to exist, the presence of an extracellular signal is required, which will activate the fusion of the vesicles.
In the case of insulin, the external signal originates with the increase in blood glucose levels, a signal that penetrates the intracellular space and generates an increase in insulin production in the islets of Langerhans (pancreas).
Before insulin secretion occurs, the cell must be depolarized, allowing calcium to enter, which promotes transport by regulated exocytosis of insulin to the extracellular space.
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