Evidence suggests that cAMP response-element-binding protein (CREB) may be a final common target of antidepressant treatment.
Antidepressant medications work by binding to a number of monoamine neurotransmitter receptors and activating the cAMP signal transduction pathway. Chronic antidepressant therapy has been linked to the cAMP signalling system. Increases in cAMP cause the cAMP response element-binding protein(CREB) to be phosphorylated more frequently via increased receptor adenylate cyclase activity .
CREB mediates transcriptional responses to increased cAMP levels by attaching to cAMP response element (CRE) sites.In order to prevent recurring episodes, treatment for depression should maintain therapeutic efficacy while also addressing behavioural symptoms and indicators of the illness. One important modulator of the transcriptional effects of antidepressants may be CREB.
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Answer:
The correct option is;
-Eccentric Contraction
Explanation:
The releasing of the muscles slowly to become longer under the effect of a load is known as eccentric contraction
An example of eccentric contraction is the elongation of the curl biceps as the load of the dumbbell is lowered down after lifting, such that while in the process of lowering rather than dropping the dumbbell down the biceps remain in contraction so as to maintain control of the descent
Along with eccentric contraction, isometric contraction and concentric contraction make up the three phases of muscles and tendon movement.
B, A, C because the people are at the tournaments for a reason. The students next because they most likely like sports and last the department store
