Answer:
1. Inhibiting IP3 channels, leading to decreased Ca2 in the sarcoplasm and reduced contraction.
2. Increasing the relative activity of MLCP, leading to a decrease in tension.
3. Activating K channels, increasing K leaking out of the cell which hyperpolarizes it and decreases the likelihood of Ca2 entry.
Explanation
In smooth muscle, cyclic AMP (cAMP) mediates relaxation because cAMP inhibits a specific kinase required for myosin light chain protein (MLCP) phosphorylation, thereby triggering contraction in the smooth muscles. It has been shown that cAMP inhibits 1,4,5-trisphosphate (IP3)-dependent calcium ions (Ca 2+) release by activation of the cGMP-dependent protein kinase (PKG). PKG proteins act to modulate Ca2+ oscillations by stimulating sarcoplasmic Ca2+-ATPase membrane proteins, increasing Ca2+ in the sarcoplasmic reticulum stores and Ca2+ efflux from the cells, and activate voltage-gated potassium (K) channels, thereby leading to membrane hyperpolarization and reducing Ca2+ entry through Ca2+ channels.
Answer:
memerintahkan kaum muslimin untuk hijrah ke habasyah(Ethiopia)
Explanation:
-Dalam rombongan pertama hijrah, yaitu pada tahub ke lima kerasulan nabi muhammad, ada 15 orang.
10 laki lakin dan 5 perempuan yang hijrah ke habasyah dibawah komando ustman bin affan, termasuk istri ustman bin affan yaitu rukyah binti muhammad
-kemudian, pada rombongan ke dua, ada sekitar 81 orang, yang terdiri dari 80 laki laki dan 1 perempuan. perempuan tersebut adalah ummu habibah yang merupakan istri dari abu sofyan
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Well 1, why would I pretend that I was a carbon atom. 2, I’m to tired to, 3, just no.
Answer:
They help you live longer
Explanation:
Research has shown that social connections not only impact your mental health, but your physical health as well. A review of 148 studies (308,849 participants) indicated that individuals with stronger social relationships had a 50% increased likelihood of survival.
Answer:
Group 1 - Alkali metals; Group 4 - Elemental Properties
Explanation:
The elements in Group 1 are called Alkali metals and those are: Lithium, Potassium, Rubidium, Celsium, Francium and Sodium and the elements in Group 4 are called: Titanium, Hafnium, Zirconium and Rutherfoundium.
It's important that group 4 has no trivial name like the group 1 does, it belongs to the grouping of <em>transition metals </em>and those metals have several general properties. They are found in the middle of the periodic table.
