When a DNA sequence alteration results in a stop codon rather than a codon that specifies an amino acid, it is known as a nonsense mutation. This is rarely seen in 10% of patients with genetic disease.
<h3>What is nonsense mutation?</h3>
A nonsense mutation in a DNA sequence causes a premature stop codon, also known as a nonsense codon, in the transcribed mRNA as well as a shortened, ineffective, and typically nonfunctional protein product.
Because stop codons, also known as nonsense codons, signal the completion of protein synthesis rather than encoding for an amino acid, they are the source of the term "nonsense mutation."
Examples of illnesses for which nonsense mutations have been implicated as contributing factors include: Cystic fibrosis (produced by the G542X mutation in the cystic fibrosis transmembrane conductance regulator); (CFTR) Beta-globin (thalassemia) Hurler disease.
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Skin serves as a protective barrier, a way to sense the world, and a layer that keeps nutrients and water inside the body. Four types of cells make up the skin, and they are produced mainly in the epidermis near the basement membrane.
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Climate change can overwhelm the capacity of ecosystems to mitigate extreme events and disturbance, such as wildfires, floods, and drought.
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The molecuels in liquid moves slower than the ones in the sun
