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raketka [301]
1 year ago
7

A scientist wishes to develop a new drug that prevents synaptic communication via neuropeptides but not small molecule neurotran

smitters. Which mechanism would be a good target for his drug
Biology
1 answer:
kirill [66]1 year ago
5 0

Disruption of axonal transport would be a good target for his drug.

<h3>What is disruption of axonal transport?</h3>
  • Axonal transport defects are among the early molecular events leading to neurodegeneration in mouse models of amyotrophic lateral sclerosis (ALS).
  • Gene expression profiles indicate that dynactin-1 mRNA is downregulated in degenerating spinal motor neurons of autopsied patients with sporadic ALS.
  • Disruption of axonal transport also underlies the pathogenesis of spinal muscular atrophy and hereditary spastic paraplegias.
  • The neurotoxin β,β′-iminodipropionitrile (IDPN) selectively disrupts slow axonal transport without affecting fast anterograde or retrograde axonal transport.
  • Impairment of slow axonal transport causes a proximal accumulation of neurofilaments.
  • Because neurofilaments regulate axonal diameter, this accumulation leads to a marked swelling of the axon.
  • Acrylamide causes decreased axonal transport, also causing proximal accumulations of neurofilaments and swelling.

To learn more about axonal transport,

brainly.com/question/10600853

#SPJ4

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Earth's biosphere is described as
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the layer of the planet Earth where life exists

Explanation:

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3 years ago
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Which of the following is a step that occurs within an inflammatory response?
natka813 [3]
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2 years ago
How is the division of the cytoplasm different in plants and in animals?
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3 0
3 years ago
PLEASE HELP ONLY 2 I CANT GET
ehidna [41]
1.) B it is not d because it shows a growth in the beak size, it didn't say anything about the birds having larger beaks just that the size increased
2.) A

p=.5 q=.5
q^2=.25 p^2= .25 2(pq)= .5  everything added up is 1.0 so we good

so q^2, which is the recessive gene or gg, is 25 percent
6 0
3 years ago
Explain the difference between sexual reproduction and asexual reproduction. Explain either an advantage or disadvantage for
ira [324]

In asexual reproduction, reproductive organs aren't used but they're used.

advantage of sexual- A lot of genetic variation. since they have DNA of two parents. they can survive more and adapt more.

disadvantage of asexual- diversity is limited. Since the organism only gets the DNA of one parent, they wouldn't be able to really survive if something happened.They would easily be extinct.

Sorry I can't really cone up with better words but I hope you get the idea. it all comes down to natural selection really if you've learned about it. Hope it helped!!!

5 0
2 years ago
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