Factors considered before an antifungal is prescribed to treat systemic fungal infections are:
- Checking previous allergic conditions which can affect the treatment.
- Possible side-effects of the drug.
- Can antifungal medicine may interact with other medicines a patient is taking.
- Checking pregnancy conditions because they may affect the fetus or breastfeeding.
Systemic fungal infections are defined as invasive fungal infections which originate at a particular place in the body but have the ability to spread to other parts as well. Examples are aspergillosis and other mold infections as a result of inhalation; candidaemia as a result of infected lines or leakage from the gastrointestinal tract.
Improper medication for systemic fungal infections can lead to Infusion-related toxicity, Nephrotoxicity, including hypokalemia, liver function abnormalities, skin rash, visual disturbances, etc.
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