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nasty-shy [4]
1 year ago
12

calcium signaling in individual app/ps1 mouse dentate gyrus astrocytes increases ex vivo with aβ pathology and age without affec

ting astrocyte network activity
Biology
1 answer:
irakobra [83]1 year ago
3 0

Astrocytes are a group  of cells with functional characteristics and distinctive morphological that vary within specific areas of the brain.

For healthy brain function, astrocytes are essential. those become reactive in the case of Alzheimer's disease, which impacts the signaling properties. while experimenting, there was the measurement for instinctive calcium transients ex vivo in hippocampal astrocytes in brain slices containing the dentate gyrus of  9-month-old  and 6-month-old APPswe/PSEN1dE9 mice. when they investigated the duration of calcium transients and frequency concerning amyloid-β (Aβ) pathology, the proximity of the astrocyte to Aβ plaques, and aging. there was no change in spontaneous calcium-transient properties of 6M APP/PS1 astrocytes compared to wild-type astrocytes, whereas there was hyperactivity in 9M APP/PS1 astrocytes compared to wild -type,  which were longer in duration, also there was an effect of aging too, there was an increase in calcium in the 9-month astrocytes than to the 6-month astrocytes, also there was an increase in the calcium waves in the 9-month astrocytes because of the increase network activity. The findings were that the change in calcium signaling in individual astrocytes of APP/PS1 mice is because of both pathology and aging but these don't have any impact on changes in the astrocyte network activity, which leads to helping to understand changes in neuronal physiology.

To know more about neuronal physiology refer to the link brainly.com/question/17060419?referrer=searchResults.

#SPJ4

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One thing all cells have in common is an ability to colonize any environment on earth.
miskamm [114]

<u>False</u>,

All cells don't have in common is an ability to colonize any environment on earth.

Cells- A cell's cytoplasm and nucleus are enclosed in a membrane, making it the smallest structural and functional component of an organism.

Environment- The natural habitat or natural world includes all living and non-living things that arise spontaneously, or in this case, without the use of artificial methods.

Living Object- A living thing is any creature or life form that demonstrates or possesses the characteristics of life or being alive.

Non-living things are inanimate items or forces that have the power to affect, shape, modify, and have an impact on the life of a living creature.

To know more about Environment, click on the below link,

brainly.com/question/1748429

#SPJ4

3 0
1 year ago
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8090 [49]
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3 years ago
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3 years ago
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Julli [10]

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One amino acid

Explanation:

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Since the mutation is a kind of substitution mutation, only the codon affected by that mutation will change. This DNA sequence will be transcribed into a mRNA sequence. The mRNA will be read codon by codon (a group of hree nucleotides) to produce amino acid. Since one codon will be involved, one amino acid will be affected.

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