Question

Regarding serum iron analysis, the maximum concentration of iron that transferrin can bind is reflected in what laboratory measurement?

Answer 1

Regarding serum iron analysis, the maximum concentration of iron that transferrin can bind is reflected in Transferrin saturation laboratory measurement.

Transferrin saturation, estimated as a percentage, is a medical laboratory measurement. It is determined by dividing the value of serum iron by the total iron-binding capacity of the accessible transferrin.

Transferrin is the major protein which binds iron in the blood and this value tells a physician how much serum iron is bound.

A low transferrin saturation is a general sign of iron deficiency anemia while a high transferrin saturation may signify iron overload or hemochromatosis.

Transferrin saturation is also known as transferrin saturation index (TSI) or transferrin saturation percentage (TS%).

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