Question

In an aqueous solution, hydrophobic interactions cause a protein to fold in a way that positions its nonpolar r groups where?

Answer 1

They are found in the interior of the protein, away from water, which preserves the entropy of water in solution.

What is entropy ?

Entropy is a measureable physical characteristic and a scientific notion that is frequently connected to a condition of disorder, unpredictability, or uncertainty. From classical thermodynamics, where it was originally recognized, through the microscopic description of nature in statistical physics, to the fundamentals of information theory, the phrase and concept are utilized in a variety of disciplines. It has numerous applications in physics and chemistry, biological systems and how they relate to life, cosmology, economics, sociology, weather science, and information systems, especially the exchange of information.

Scottish scientist and engineer Macquorn Rankine first used the terms thermodynamic function and heat potential to describe the thermodynamic notion in 1850.

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