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kodGreya [7K]
1 year ago
14

with the increased risk of drug toxicity among chronically ill older adults, which statement by the nurse explains why the older

adult's kidney is vulnerable to toxic injury?
Medicine
1 answer:
gayaneshka [121]1 year ago
7 0

A role of nitric oxide (NO) in the increased sensitivity of the aging kidney to injury has been established.

<h3>What is drug toxicity ?</h3>

Drug toxicity is characterised as a wide range of negative effects brought on by the use of drugs at therapeutic or non-therapeutic dosages.

  • The rate of cellular apoptosis in the kidney increases with age, resulting in fewer functional nephrons and a decrease in GFR and creatinine clearance ratio. This decrease in renal functional reserve makes the kidney more vulnerable to AKI.

  • The mechanisms-based (on-target) toxicity, immunological hypersensitivity, off-target toxicity, and bioactivation/covalent modification are a few of the causes of drug toxicity that can be grouped in different ways.

Learn more about Drug toxicity here:

brainly.com/question/2867251

#SPJ4

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