Question

with the increased risk of drug toxicity among chronically ill older adults, which statement by the nurse explains why the older adult's kidney is vulnerable to toxic injury?

Answer 1

A role of nitric oxide (NO) in the increased sensitivity of the aging kidney to injury has been established.

What is drug toxicity ?

Drug toxicity is characterised as a wide range of negative effects brought on by the use of drugs at therapeutic or non-therapeutic dosages.

• The rate of cellular apoptosis in the kidney increases with age, resulting in fewer functional nephrons and a decrease in GFR and creatinine clearance ratio. This decrease in renal functional reserve makes the kidney more vulnerable to AKI.

• The mechanisms-based (on-target) toxicity, immunological hypersensitivity, off-target toxicity, and bioactivation/covalent modification are a few of the causes of drug toxicity that can be grouped in different ways.

Learn more about Drug toxicity here:

brainly.com/question/2867251

#SPJ4