The stability was significantly raised by changing T286 to alanine (T286A).
<h3>What occurs when phosphorylation of a protein occurs?</h3>
A protein's structural shape is changed by phosphorylation, activating or deactivating it or otherwise changing how it performs. Human proteins have phosphorylation at over 13000 different places.
<h3>How does phosphorylation impact the way proteins work?</h3>
Protein activity, stability, protein interaction, and subcellular localization can all be sensitively and dynamically controlled by phosphorylation. Multiple kinases frequently target global regulators, changing how many genes are expressed.
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