Question

Active tissues that are metabolizing quickly only have a PO2 of 20 mm Hg. How much hemoglobin is saturated at this point? Why is it beneficial for the hemoglobin near these tissues to NOT pick up oxygen?

Answer 1

The percentage of hemoglobin that will be saturated when the PO2 is 20 mmHg is 20%.

Why is it beneficial for the hemoglobin near these tissues to NOT pick up oxygen?

It is recommended that the tissues do not absorb oxygen at this point because the affinity of hemoglobin for oxygen will be low since the medium will be acid due to the amount of hydrogen ions and carbon dioxide, situation that occurs in tissues where oxygen is metabolized quickly. Therefore, then there will be no absorption of oxygen from these tissues, but rather it will occur in oxygenated tissues such as the lungs. This is an effect called the 'Bohr effect' and allows oxygen to be released where it is most needed.

And the percentage of oxygen saturation will be 20% according to the hemoglobin saturation curve.

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