Question

Which type of mutation in the DNA sequence would cause the most change in the amino acid sequence?

Answer 1

Frameshift mutations  type of mutation in the DNA sequence would cause the most change in the amino acid sequence.

• The outcome of a frameshift mutation is complete alteration of the amino acid sequence of a protein.
• This alteration occurs during translation because ribosomes read the mRNA strand in terms of codons, or groups of three nucleotides.

What type of mutation causes the most change in an amino acid sequence?

• Missense: A missense variant is a sort of substitution in which a nucleotide change causes the protein produced from the gene to have a different amino acid in place of one amino acid.
• The protein's functionality could be affected by the amino acid alteration.

What is a major mutation?

• The Major mutation framework supports both fundamental research on mutation testing and effective mutation analysis of big software systems.

• The three elements that Major offers are as follows: Mutator built into the compiler enabling quick and simple fault seeding.
• To precisely configure the mutation process, use domain-specific language.

Learn more about frameshift mutation

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