Some activated b cells will move to the follicles where, with the aid of follicular t helper cells in the spleen and lymph nodes, they continue to differentiate.
<h3>B-cell differentiation: </h3>
In reaction to the antigens, these cells develop in the bone marrow and create antibodies. Humoral reaction involves B lymphocytes. B cells create plasma cells and memory B cells as soon as they come into contact with the antigens.
In the spleen and lymph nodes, B-cells develop into plasma cells. An immunoglobulin receptor on each B-cell can bind to a single, distinct, unprocessed antigen. After being exposed to an antigen, B cells release interleukins to become active.
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