Yes, 2,4-dinitrophenol (DNP) was first used on factory workers in the 1930s and it helped them lose weight.
Explanation:
2,4-dinitrophenol (DNP):
DNP is an anti-obesity drug that works by shuttling the movement of protons across the mitochondrial membrane, shifting the electrochemical gradient. This process is called uncoupling oxidative phosphorylation.
Uncoupling oxidative phosphorylation increases the body's metabolic rate and inhibits the production of ATP through oxidative phosphorylation. This forces the body to produce ATP by metabolizing stored fat.
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