Question

2,4-Dinitrophenol (DNP) is a drug that can shuttle protons across biological membranes. In the 1930s it was used as a diet pill. Do you think this drug was effective in helping people to lose weight?

Answer 1

Answer:

Yes, 2,4-dinitrophenol (DNP) was first used on factory workers in the 1930s and it helped them lose weight.

Explanation:

2,4-dinitrophenol (DNP):

• DNP is an anti-obesity drug that works by shuttling the movement of protons across the mitochondrial membrane, shifting the electrochemical gradient. This process is called uncoupling oxidative phosphorylation.
• Uncoupling oxidative phosphorylation increases the body's metabolic rate and inhibits the production of ATP through oxidative phosphorylation. This forces the body to produce ATP by metabolizing stored fat.