The answer that you are looking for is A. Nephrons
Joes way of hanging out with the wrong people can be a big factor of the problem with his substance addiction
Myocardial infarction, the medical term for heart attack, literally means "heart tissue damage or death.". Heart attacks most commonly occur when one or more of the coronary arteries — a network of blood vessels that supply blood to the heart — become blocked. Heart muscle becomes starved for oxygen and nutrients.
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The differnce between the two is from person to person it is by bodily fluids and environmental is through or could be an airborne diesease
I believe the answer is the Exhaustion stage because it is the bodies reaction to stress. The body becomes extremely susceptible to sickness because it seems to lose to respond to any new stress. Hope I helped!