Monogenetic disorders are caused by a mutation in a single gene. The mutation may be present on one or both chromosomes (one chromosome inherited from each parent). Examples of monogenic disorders are: sickle cell disease, cystic fibrosis, polycystic kidney disease, and Tay-Sachs disease.
Delta is a type of fibre that transmits signals that are interpreted and perceived as pain.
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Delta fibres</h3>
A delta fibres (also known as A fibres) are a type of sensory fibre. They respond to cold and pressure stimuli, and as nociceptors, their stimulation is perceived as fast/first pain input. Because they are thinly myelinated, they transmit impulses quicker than unmyelinated C fibres but slower than other, thicker myelinated "A" class fibres.
Structure
They have myelinated axons that are thin (2 to 5 m in diameter) and have a moderate conduction velocity, or speed at which a nerve signal moves (2 to 30 m/s). These nerve fibres make up the afferent portion of the reflex arc that causes the body to "draw away" from noxious stimuli because they are linked to acute (sharp) pain (e.g. retracting your hand away from a hot stove). A part of A fibres is also linked to pressure and temperature perception (also known as "cold receptors" in mammals). Contrarily, slow-conducting, unmyelinated C fibres convey gradual, scorching pain.
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-are more likely to develop post traumatic stress disorder
