Attachment of acetyl groups to histone promotes transcription.
This mechanism is known as histone acetylation and it is a part of gene expression. The lysine residues inside the N-terminal tail from the histone core of the nucleosome are the substrate for enzymes-histone acetyltransferase which transfer an acetyl functional group from another molecule. Acetylation removes the positive charge on the histones and thus decrease the interaction negatively charged phosphate groups of DNA. As a result, chromatin becomes more relaxed structure and transcription is promoted.
<span>The nurse needs to teach the client to remove loose rugs from their environment. As a patient in clutches, one of their main risk factors is slippage around their environment which may cause further damage to their body or undo the treatment that had already been done to their tibia and fibula.</span>
