Tissue damage activates nociceptors or pain receptors in the skin. A signal is sent to the peripheral nerve to the spinal cord where neurotransmitters or chemical messengers are released. It activates other nerves to pass signal to the brain. The signals are relayed to the somatosensory cortex for sensation, frontal cortex for thinking and limbic system for emotional response.
Yes.You can change its inside or outside
My neighbor has one that screams its hilarious!
