Answer:
Four possible isomers (1–4) for the natural product essramycin. The structure of compound 1 was attributed to essramycin by 1H NMR, 13C NMR, HMBC, HRMS, and IR experiments.
Explanation:
Three synthetic routes were used to prepare all four compounds (Figure 2A). All three reactions utilize 2-(5-amino-4H-1,2,4-triazol-3-yl)-1-phenylethanone (5) as the precursor, whereas each uses different esters (6–8) to construct the pyrimidinone ring. Isomer 1 was prepared by reaction A, which used triazole 5 and ethyl acetoacetate (6) in acetic acid. This was the reaction used in syntheses of essramycin by the Cooper and Moody laboratories.3,4 Reaction B produced compound 2 (minor product) and compound 3 (major product), which were separated chromatographically. This reaction allowed reagent 5 to react with ethyl 3-ethoxy-2-butenoate (7) in the presence of sodium in methanol, under reflux for 24 h. Compound 4 was prepared by reaction C, which was obtained by reflux of 5 and methyl 2-butynoate (8) in n-butanol.
Answer:
Oxygen is not released into the atmosphere
-The marine sediments are formed into rocks by Earth's geologic processes
Answer:
inches of mercury (inHg or “Hg) or millibars.
Answer:
part (a) was used to calculate the molar mass of the metal M. In part (c) students proposed an experimental test that could be used to determine if MI 2 is an ionic solid, and then explained how the results of the test supported this claim. Students explained why I 2 is solid at room temperature, but Br 2 is a liquid in part (d). its {c}
Answer:
B - The high temperature makes the gas molecules spread apart according to Charles's law because this law describes how a gas will behave at constant pressure.
Explanation:
Charle's Law describes the relationship between temperature and volume, where increased temperature leads to increased volume. When volume is increased, that means the gas molecules are more spread apart and have more random motion. Therefore, the answer is B.