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what are some examples of environmental concerns or issues
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An organic mental disorder is a previously used term to describe a dysfunction of the brain that was meant to exclude psychiatric disorders. It is currently known under the category of neurocognitive disorders. It describes reduced brain function due to illnesses that are not psychiatric in nature.
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<em>Hepatitis B
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Herpes B Virus is a very severe and often lethal transmittable disease that macaque monkeys can carry and transmit.
In a <em>primate lab animal environment, it is the infection of major concern.</em>
This induces neurological symptoms and for humans it can have a mortality rate of about 80%.
Transmission may be caused by bites, scratches, or contact to mucous membranes, including the eyes or mouth with contaminated saliva.
Disorder and an illness don’t quote me on that though
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Multiple sclerosis (MS) is the most common demyelinating and an autoimmune disease of the central nervous system characterized by immune-mediated myelin and axonal damage, and chronic axonal loss attributable to the absence of myelin sheaths. T cell subsets (Th1, Th2, Th17, CD8+, NKT, CD4+CD25+ T regulatory cells) and B cells are involved in this disorder, thus new MS therapies seek damage prevention by resetting multiple components of the immune system. The currently approved therapies are immunoregulatory and reduce the number and rate of lesion formation but are only partially effective. This review summarizes current understanding of the processes at issue: myelination, demyelination and remyelination—with emphasis upon myelin composition/architecture and oligodendrocyte maturation and differentiation. The translational options target oligodendrocyte protection and myelin repair in animal models and assess their relevance in human. Remyelination may be enhanced by signals that promote myelin formation and repair. The crucial question of why remyelination fails is approached is several ways by examining the role in remyelination of available MS medications and avenues being actively pursued to promote remyelination including: (i) cytokine-based immune-intervention (targeting calpain inhibition), (ii) antigen-based immunomodulation (targeting glycolipid-reactive iNKT cells and sphingoid mediated inflammation) and (iii) recombinant monoclonal antibodies-induced remyelination.Keywords: calpain, central nervous system, demyelination, fingolimod, glycolipids, lipids, multiple sclerosis, myelin, myelination, NKT cells, oligodendrocytes, remyelination, T cells
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